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FAQ
What is MRI and how does it work?
What is involved in a treatment?
Who determines if radiosurgery is appropriate?
What does the amount of radiation time mean?
For what is the Gamma Knife used?
How is safety ensured?
How long is the treatment?
How does the Gamma Knife work?
What about the radiation risk?
Why is it called surgery?
How long will my Gamma Knife Treatment take?
Will I experience any pain during the procedure?
What is Stereotactic Radiosurgery (SRS)?
What can the Gamma Knife treat?


What is MRI and how does it work?

Magnetic resonance imaging, or MRI, is a way of obtaining very detailed images of organs and tissues throughout the body without the need for x-rays. Instead, it uses a powerful magnetic field, radio waves, a rapidly changing magnetic field, and a computer to demonstrate whether or not there is an injury or some disease process present. For this procedure, the patient is placed within the MR scanner—typically a large, tunnel or doughnut-shaped magnet that is open at both ends. The magnetic field aligns atomic particles called protons that are present in most of the body's tissues. Radio waves then cause these particles to produce signals that are picked up by a receiver within the scanner. The signals are specially characterized using the changing magnetic field, and computer-processed to create very sharp images of tissues as "slices" that can be viewed in any plane or from any direction.

An MRI exam causes no pain, and the magnetic fields produce no known tissue damage of any kind. The MR scanner may make loud tapping or knocking noises at times during the exam; using earplugs prevents problems that may occur with this noise. You will be able to communicate with the technologist or radiologist at any time using an intercom.


How safe is MRI?

The powerful magnetic field of the MR system will attract iron-containing (also known as ferromagnetic) objects and may cause them to move suddenly and with great force. This can pose a possible risk to the patient or anyone in an object's flight path. Great care is taken to be certain that objects such as "ferromagnetic" screwdrivers and oxygen tanks are not brought into the MR system area. It is vital that you remove any metallic belongings in advance of an MRI exam, including watches, jewelry, and items of clothing that have metallic threads or fasteners.

The powerful magnetic field of the MR system will pull on any iron-containing object in the body, such as certain medication pumps or aneurysm clips. Every MRI facility has a protocol that, when carefully followed, will ensure that the MRI technologist and radiologist knows about the presence of metallic implants and materials so that special precautions can be taken. In some unusual cases the exam may have to be canceled. An example is MRI of the head when a "ferromagnetic" aneurysm clip is present, because there is a risk of the clip moving or being dislodged. The magnetic field may damage an external hearing aid or cause a heart pacemaker or electrical stimulator to malfunction. If you have a bullet or other metallic fragment in your body there is a potential risk that it could change position, possibly causing injury.

A metallic implant or other object may distort the MR images or make it difficult for the MRI system to "tune" to your body. This may be unavoidable, but if the radiologist knows about it, allowance can be made when interpreting the images.

For some MRI studies a contrast material called gadolinium may be injected into a vein to help interpret the exam. Unlike contrast agents used in x-ray studies, a gadolinium contrast agent does not contain iodine and therefore rarely causes an allergic reaction or other problem.

How will I prepare for my MRI exam?

You will typically receive a gown to wear during your MRI study. Before entering the examining room, any friend or relative accompanying you will be asked questions regarding the presence of implants and will be instructed to remove all metal objects from pockets and hair. Additionally, this individual will need to fill out a screening form to ensure that he or she may safely enter the MR system room.

Before the exam you will be asked to fill out a screening form asking about anything that might create a health risk or interfere with imaging. Items that may create a health hazard or other problem during an MRI exam include:

  • Cardiac pacemaker or implantable defibrillator
  • Catheter that has metal components that may pose a risk of a burn injury
  • A metal clip placed to prevent bleeding from an intracranial aneurysm
  • A medication pump (such as that used to deliver insulin or a pain-relieving drug)
  • A cochlear (inner ear) implant

Items that need to be removed by patients and individuals before entering the MR system room include:

  • Purse, wallet, money clip, credit cards, cards with magnetic strips
  • Electronic devices such as beepers or cell phones
  • Hearing aids
  • Metal jewelry, watches
  • Pens, paper clips, keys, coins
  • Hair barrettes, hairpins
  • Any article of clothing that has a metal zipper, buttons, snaps, hooks, underwires, or metal threads
  • Shoes, belt buckles, safety pins

Objects that may interfere with image quality if close to the area being scanned include:

  • Metallic spinal rod
  • Plates, pins, screws, or metal mesh used to repair a bone or joint
  • Joint replacement or prosthesis
  • Metal jewelry such as that used with body piercing.
  • Some tattoos or tattooed eyeliner (these alter MR images, and there is a chance of skin irritation or swelling; black and blue pigments are the most troublesome)
  • Bullet, shrapnel, or other type of metal fragment
  • Metallic foreign body within or near the eye (such an object generally can be seen on an x-ray; metal workers are most likely to have this problem)
  • Dental fillings (while usually unaffected by the magnetic field, they may distort images of the facial area or brain; the same is true for orthodontic braces and retainers)

The question of claustrophobia

Some patients who have MRI in an enclosed scanner may feel confined, closed-in, and frightened. Perhaps one in twenty will require a sedative to remain calm. Today, many patients avoid this problem when examined in one of the newer MRI units that have a more "open" design. Some MRI centers permit a relative or friend to be present in the MR system room, which also has a calming effect. If patients are properly prepared and know what to expect, it is almost always possible to complete the examination even if a conventional MRI system is used.


Pregnancy and MRI

In general, there is no known risk of using MRI in pregnant patients. However, MRI is reserved for use in pregnant patients only to address very important problems or suspected abnormalities. In any case, MRI is very likely safer for the fetus than imaging with x-rays.

You should be sure to inform your radiologist if you are breast-feeding at the time of a scheduled MRI study and are to receive an MR contrast agent. One option under this circumstance is to pump breast milk before the study, to be used until injected contrast material has cleared from the body, which typically takes about 24 hours.


The MRI safety information on this page was developed in cooperation with the Institute for Magnetic Resonance Safety, Education, and Research from content on www.MRIsafety.com.

For more detailed MRI safety information, visit www.MRIsafety.com, which provides up-to-date and crucial MRI safety information, especially for screening patients with implants and medical devices.

What is involved in a treatment?

On the day of treatment, the patient will have a lightweight frame attached to the head. Local anesthesia is used before the frame is secured in place. The frame is used in conjunction with an imaging procedure to accurately locate the diseased area. With the frame in place, the patient has either an MRI or CT imaging study or, in the case of AVM, angiography, in order to precisely locate the diseased area to be treated. Data from the imaging study is transferred into the treatment planning computer. While the patient rests, the treatment team used advanced software to determine the treatment plan. This takes one or two hours to complete depending on the complexity and location of the disease. When the individual treatment plan is completed, the patient is placed on the couch and precisely positioned. The patient is then moved automatically, head first into the machine, and treatment begins. Treatment typically lasts from 15 minutes to an hour, during which time the patient feels nothing unusual. At the completion of the treatment the patient is automatically moved out of the machine, and the head frame is removed. The patient may remain in the hospital overnight for observation.
Who determines if radiosurgery is appropriate?

Medical necessity can be determined by a neurosurgeon, radiation oncologist or other medical specialist after evaluating a prospective patient抯 medical condition. Treatment options are then determined and discussed with the patient and family, so an informed decision may be made.
What does the amount of radiation time mean?

Full Question: I have a small acoustic neuroma and my friend抯 wife has a larger one. We both had radiosurgery at different hospitals. When we were talking, she said she had less time in the machine than I did. Did I get too much radiation?

The treatment time is a factor of the dose given and the half-life of the cobalt60 in the treating machine. Apparently, the machine you were treated on had cobalt60 that was older and required more time to 揺mit?the dose required to you appropriately. The half-life of cobalt60 is 5.26 years. This means the same treatment given when the cobalt was fresh would take twice as long to give 5.26 years later.
For what is the Gamma Knife used?
The Gamma Knife is used to treat brain metastases (tumors that started in the body and spread to the brain) such as lung cancer, breast cancer, melanoma, etc. It is used to treat benign tumors such as meningiomas and acoustic neuromas. It is also used for treatment of Arteriovenous Malformations (AVMs). The pain syndrome of trigeminal neuralgia, and the tremor of Parkinson’s disease may also be treated with Gamma Knife. Finally, the most malignant tumors of the brain, the glioblastoma multiforme, or anaplastic astrocytomas, as well as a number of other primary tumors of the brain, can be treated.
How is safety ensured?

 

Because placement accuracy of the shots is critical to localization of the radiation (to the fraction of a millimeter) anything that would degrade this precision is unacceptable. Rigid attachment of the headframe, geographic targeting accuracy of the MRI, shaping of the volume of tissue to be treated (selection of the number, size and relative intensity of the shots) and accuracy of attachment of the frame to the gamma knife unit are all critical. As is true of all radiation therapy, correct selection and calculation of the amount of radiation to deliver are essential. A qualified medical physicist assures that the imaging and treatment planning computers and software are correct and acceptable. The mechanical functions of the machine are tested on a regular basis to ensure the safety of patients and medical staff.

How long is the treatment?

The treatment starts early in the morning (usually 6:30 a.m.) and is over by noon. After the procedure, the patient eats lunch and is then able to be discharged home or admitted overnight for observation, depending upon the clinical condition being treated. The actual time inside the Gamma Knife varies from about 10 minutes to 90 minutes.

How does the Gamma Knife work?
For tumors, the very intense dose of radiation directed precisely to the tumor, causes the DNA and proteins in the cell to render themselves unable to divide. The tumor cells can then no longer live, and slowly die over time. The waste is then removed by circulating white blood cells. For AVMs, the radiation causes the blood vessels to thicken and scar until flow ceases. For trigeminal neuralgia, the protective covering or insulation around the pain nerves is destroyed, thus making the nerve unable to conduct an impulse of pain.
What about the radiation risk?
The dose of radiation is extremely focused to the target in the brain and the dose outside the target is very low.
Why is it called surgery?
Radiosurgery (one-session treatment) has such a dramatic and precise effect in the target zone that the changes are considered ‘surgical’. Through the use of three-dimensional computer-aided planning and the high degree of immobilization of the patient, the treatment can minimize the amount of radiation to surrounding healthy brain tissue. Gamma Knife® precision is submillimeter. Stereotactic radiosurgery is routinely used for brain tumors and lesions. It may be the primary treatment; utilized where a tumor is inaccessible by surgical means; or as a boost or adjunct to other treatments with a recurring or malignant tumor.
How long will my Gamma Knife Treatment take?

A typical treatment will takes approximately 4 hours to complete.  During this time you will feel no pain and you will be able to listen to your favorite music while the treatment is being performed.
Will I experience any pain during the procedure?

The Gamma Knife is the "gold standard" in the treatment of lesions in the brain by a noninvasive surgical technique called stereotatic radiosurgery.  It is a safe, precise, bloodless procedure.  The beams are precisely aimed so as to treat only the target (tumor, trigeminal nerve, etc.) with minimal risk to adjacent brain structures.
What is Stereotactic Radiosurgery (SRS)?

Stereotactic Radiosurgery treats brain disorders by delivering a single high dose of radiation in a one-day session. Treatment involves the use of focused radiation beams delivered to a specific area of the brain to treat abnormalities, tumors or other functional disorders. 
What can the Gamma Knife treat?
 
        Brain Cancers and Tumors:
Brain metastases
Chordoma
Craniopharyngioma
Glioma
Hemangioblastoma
Meningioma
Pineal tumors
Pituitary adenoma
        Vascular Disorders:
Arteriovenous malformations (AVM)
Arteriovenous fistulas (AVF)
Cavernomas
        Functional Disorders:
Trigeminal neuralgia
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